“School of Nano-Sciences”
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| Paper IPM / Nano-Sciences / 17755 |
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In neurophysiological recording, reducing electrode impedance is crucial for enhancing the signal-to-noise ratio
and achieving the desired spatial resolution. This study presents an approach to improve the performance of Au/
Cr/glass electrodes by incorporating synthesized gold nanosheets without the need for additional adhesive
material. We characterized the performance of the modified electrodes using electrochemical impedance spectroscopy and equivalent circuit analysis. Our findings showed an 81% reduction in mean impedance for the
modified electrode, which was 0.85 kΩ at 1 kHz, compared to the unmodified electrode at 4.5 kΩ, an
improvement attributed to the higher effective surface area of the modified electrode. Additionally, Scanning
electron microscopy observations of PC12 cells cultured on the modified electrodes indicated favorable cell
elongation and interaction with the rough surface. Stability studies indicated acceptable performance of the
modified electrodes in solution environments. These results suggest that surface modification of electrodes with
gold nanosheets could be a promising strategy for enhancing neural interface applications.
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