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Paper IPM / Cognitive / 12172 |
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Background/aims: Both histamine and nitric oxide (NO) may play a role in anxiety-like behavior. Within the brain, the amygdala is an important area involved in processing emotional responses such as anxiety. The aim of the present study was to assess whether the NO system in the basolateral amygdala (BLA) influences histamine-induced anxiety-like behavior in rats. Methods: Male Wistar rats weighing 200?220 g were used. Bilateral cannulae were implanted in the BLA place for microinjections of drugs and the elevated plus maze apparatus has been used to test parameters (
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