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Paper   IPM / Cognitive Sciences / 11822
School of Cognitive Sciences
  Title:   Effect of reversible inactivation of reuniens nucleus on memory processing in passive avoidance task
1.  Farzaneh Ghiafeh Davoodi
2.  Fereshteh Motamedi
3.  Esmaeil Akbari
4.  Elham Ghanbarian
5.  Jila Behzadi
  Status:   Published
  Journal: Behav Brain Res
  Vol.:  221
  Year:  2011
  Pages:   1-6
  Supported by:  IPM
The reuniens nucleus (RE) is the largest nucleus of the midline thalamic nuclei (MLN). RE has strongly connections with the amygdala and hippocampus, the structures that are involved in the learning and memory processes. In our previous report we have shown the role of RE in the spatial learning and memory using Morris water maze (MWM) task. Since RE is connected to multiple limbic structures, its involvement in the emotional learning and memory is a possibility. The present study was designed to elucidate the role of RE in acquisition, consolidation, and retrieval on the passive avoidance (PA) task which depends on a distributed network including the thalamus, amygdala, medial prefrontal cortex (mPFC) and hippocampus. For this purpose, rats were chronically implanted with a cannula aimed at the RE through which 0.5 Ul tetracaine (2

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